Anti-epilepsy drug preserves brain function after stroke

Anti-epilepsy drug preserves brain function after stroke | EurekAlert! Science NewsTaken from the article (linked) above:In the study, one dose of the anti-epilepsy drug, retigabine, preserved brain tissue in a mouse model of stroke and prevented the loss of balance control and motor coordination. Researchers from the School of Medicine at The University of Texas Health Science Center at San Antonio conducted the study, which was published Feb. 3 in The Journal of Neuroscience.Balance and coordination testHours after a stroke, both treated mice and a control group of mice were placed on a balance beam to observe motor coordination. The untreated mice displayed a pronounced loss of coordination with slips and falls. Treated mice had no difficulty with balance, ambulation or turning around on the beam."You couldn't even tell they had a stroke," said senior author Mark S. Shapiro, Ph.D., professor of physiology at the UT Health Science Center San Antonio. "They ran across the balance beam like gymnasts."Histological analysis of the brain tissue of treated mice showed significantly reduced damage to the tissue after the stroke, compared to untreated mice. The protective effects of the medication were observed in treated mice up to five days after the stroke, said Sonya Bierbower, Ph.D., postdoctoral fellow and lead author of the report.-------------------------------------------------------------------------------------------------------------------Worth a read for all of you fellow neuroscience fanatics. The article by Bierbower et al. (2015) looks at how specific anti-epilepsy medication can reduce impact of strokes. Check it out!-BR>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>References:Picture from http://www.medicalnewstoday.com/images/articles/007/7624/skull-with-red-to-indicate-stroke.jpg

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