How Do SNRIs Work For Anxiety?

Selective serotonin-norepinephrine reuptake inhibitors, or SNRIs, are a type of antidepressant often prescribed for anxiety disorders. They are a recently introduced class of antidepressants but are among the most widely prescribed. SNRIs work by increasing levels of the neurotransmitters serotonin and norepinephrine in the brain and are often compared to selective serotonin reuptake inhibitors (SSRIs), a similar class of antidepressants that increases brain levels of serotonin.

Because SNRIs are a newer class of drug than the other antidepressants, such as SSRIs, tricyclics, and MAOIs, there are not as many different SNRI medications available. The first FDA-approved SNRI was Effexor, which was introduced in the early 1990s and is currently approved by the FDA to treat generalized anxiety disorder, panic disorder, and social anxiety disorder, as well as major depression. Today it is the most commonly prescribed SNRI, usually in its extended-release form (Effexor XR). Other SNRIs approved by the FDA include Cymbalta and Pristiq.

SNRIs share many of the same side effects with SSRIs, with some of the most common being changes in appetite, insomnia, nausea, drowsiness, dizziness, dry mouth, and reduced sexual desire or difficulty reaching orgasm. They appear to be as or more effective than SSRIs and offer some additional choices to anxiety sufferers looking for the best medication for their situation.

Photo: LibreShot

Anxiety Support Groups

More Articles

A couple dozen people are waiting to board a plane, and at the last minute the flight is delayed...

One person immediately runs up to the...

The adrenal glands, located above the kidneys, produce a variety of essential hormones. When these glands don't produce enough of one or more of...

An article from Prevention provides a list of 6 strange physical symptoms of stress that you may not even associate with too much stress in your...

The precise causes of hoarding are unknown, but it appears that both genetics and environmental factors play a role. Because hoarding behaviors...

The terms panic attack and anxiety attack are used interchangeably by most people, but are panic and anxiety really the same thing?

Panic...

More Articles

Relationship anxiety is excessive worry about either forming or keeping a relationship. And it is considered one aspect of social anxiety disorder...

Feelings of anxiety and stress cause a number of physical and chemical changes in the body, including the release of adrenaline and other hormones...

Panic is real, and panic disorder is considered to be an illness. A panic attack is very painful and feelings of depression and helplessness may...

Cortisol is a steroid hormone that is produced in response to stress, and it is a necessary part of the fight or flight response that helps the...

Having an anxiety disorder can seriously debilitate your quality of life. If you’re suffering from anxiety, you know that it can affect your...

Anxiety levels can be affected by a number of different physiological disorders, including the common sleep disorder known as sleep apnea....

One thing to remember before a first date is that the overall quality of your life does not hinge on its success. If the date goes belly-up, you...

A report in Brain, Behavior, and Immunity concludes that consumption of omega-3 fatty acids may reduce inflammation and reduce anxiety. The study...

When we give to others, more so than receive, we are happier and more fulfilled, which can help treat anxiety and depression. A recent study,...

Sometimes the best antidote to anxiety is the humor of Woody Allen. He has a genius for turning thoughts that make us quake with fear into ideas...

Everyone is so busy these days with the demands of work, parenting, and life's everyday tasks. But you can get through the day with less stress,...

Post-traumatic stress disorder (PTSD) has received a fair amount of media and research attention lately, with the return of soldiers fighting in...

Vivactil (generic: protriptyline) is a tricyclic antidepressant that is sometimes prescribed to treat anxiety disorders such as panic disorder,...

By definition, social anxiety disorder (SAD) is an overwhelming physical and mental response to everyday social interactions, one that generally...

Two new studies shed light on the link between digestive irritation and anxiety, suggesting that physical digestive problems may cause...