Side Effects Overview of Parnate

The monoamine oxidase inhibitor (MAOI) tranylcypromine (brand name: Parnate) is an antidepressant sometimes used for the treatment of anxiety disorders. Like all medications, Parnate has the potential for side effects even when taken as directed.

Initially introduced in the U.S. in 1961, it was withdrawn from the market for a short time due to the serious side effect of high blood pressure that was fatal for some patients. It was soon reintroduced with more specific warnings and limited indications for use. While MAOIs are rarely the first medication used for depression and anxiety disorders due to their potential adverse effects, most people tolerate them fairly well and they are proven to be effective.

Side effects of tranylcypromine can include constipation, diarrhea, dry mouth, stomach pain, tremors, nausea, weakness, trouble sleeping, hypertension or hypotension, increased sweating, and changes in behavior or mood (such as feelings of anxiety, nervousness, irritability or hostility, impulsivity, or thoughts of suicide).

With all MAOIs, eating foods high in tyramine can lead to dangerously high blood pressure. Symptoms of this life-threatening situation include sudden and severe headache, confusion, blurred vision, problems with speech or balance, nausea, vomiting, chest pain, seizure, and sudden numbness or weakness.

Photo: Pexels

More Articles

According to research published in the journal Science, the drug ketamine can repair brain cell connections that have been disrupted by depression...

A recent study on anxiety and exercise found better results with resistance training than with aerobic exercise, despite the fact that most of the...

Relationship anxiety is excessive worry about either forming or keeping a relationship. And it is considered one aspect of social anxiety disorder...

A couple dozen people are waiting to board a plane, and at the last minute the flight is delayed...

One person immediately runs up to the...

Findings by researchers from Michigan State University adds to the growing evidence that links a common parasite to suicide attempts.

The...

More Articles

Psychological problems associated with nausea and vomiting include anxiety nausea. Nausea and vomiting are, in most cases, harmless....

There is a research study getting some press now about the effect of helicopter parenting on the anxiety level of children. A helicopter parent is...

Tenormin (known generically as atenolol) is a beta blocker often used to control the physical symptoms of anxiety. Beta blockers are quite...

People who spend much of their days in meetings have something to worry besides boredom, according to a study released by the Human Neuroimaging...

Some people with panic disorder have a pretty good idea about when a panic attack is likely--they know to expect one as the result of a certain...

Specific phobias are the most common type of anxiety disorder that is defined as an irrational fear of or aversion to a situation or specific...

It has already been shown many times that adults with mental illnesses often had poor cognitive skills in their youth. What hasn't been...

Prior research into obsessive-compulsive disorder (OCD) has found it very difficult to conclusively prove the link between hypersensitivity and...

How should this anxiety medication be used?

Xanax or Alprazolam, comes as a tablet to take by mouth. It usually is taken two or...

Death anxiety is the fear we experience when contemplating or facing our own mortality. Like much of our anxiety, it is an anticipation of pain...

Ludiomil (generic: maprotiline) is a tetracyclic antidepressant used for the treatment of depression and anxiety. As with any medication, there...

If it seems nearly impossible to get something off your mind, your anxiety might be out of control. Getting a handle on your anxiety will allow...

Not all causes of anxiety require a therapist; if you suffer from anxiety there are ways to self-help. And acknowledging that you have an anxiety...

Royce White has never been one to let obstacles get in the way of his dreams. An inspiring young man and stellar athlete, White was drafted by the...

Part of going to school is taking tests, and you may be one of many students that experience intense test anxiety. This performance anxiety comes...